CBDV Guide 2025: Benefits, Research & Anti-Nausea Effects

If you’ve been following the cannabinoid wellness space, you’ve probably heard of CBD, THC, and maybe even CBG. But there’s a lesser-known compound quietly making waves in clinical research: CBDV (Cannabidivarin). This non-psychoactive cannabinoid is emerging as a powerhouse for nausea relief, seizure management, and autism spectrum research.

While CBD dominates the wellness market, CBDV offers unique therapeutic properties that set it apart—particularly its impressive antiemetic (anti-nausea) effects and its potential to address conditions where CBD falls short. Let’s dive deep into what makes CBDV the cannabinoid you should know about in 2025.

CBDV, or Cannabidivarin, is a non-intoxicating cannabinoid found naturally in the cannabis plant. It’s a close molecular cousin of CBD (cannabidiol), sharing a nearly identical structure with one key difference: CBDV has a shorter side chain. While CBD has a 5-carbon (pentyl) side chain, CBDV has a 3-carbon (propyl) chain. This seemingly small difference significantly affects how the compound interacts with your body’s endocannabinoid system.

Unlike CBD, which is abundant in cannabis plants, CBDV occurs in much smaller concentrations. You’ll find trace amounts in quality full-spectrum CBD products, where it contributes to the entourage effect—the synergistic interaction between cannabinoids that enhances their collective benefits.

While CBDV and CBD share similar therapeutic profiles, their differences make each uniquely suited for specific applications. Both are non-psychoactive and interact with the endocannabinoid system, but they don’t work in exactly the same way.

The key takeaway? CBDV is being explored primarily for neurological conditions—epilepsy, autism spectrum disorders, and muscular dystrophy—while CBD has broader applications in mental and physical wellness. If you’re already using CBD products like our Anti-Stress Broad Spectrum CBD Oil, you may be getting trace amounts of CBDV as part of the entourage effect.

CBDV research has accelerated dramatically in recent years, with pharmaceutical giant GW Pharmaceuticals (now Jazz Pharmaceuticals) leading the charge. Their compound GWP42006 is a purified CBDV formulation currently in clinical trials for multiple neurological conditions.

While CBDV research is still evolving, several therapeutic applications have emerged from clinical and preclinical studies. Here’s what the science tells us:

One of CBDV’s most promising applications is as an antiemetic (anti-nausea) agent. Unlike THC, which can help with nausea but causes intoxication, CBDV offers similar antiemetic benefits without any psychoactive effects.

A 2013 study published in the British Journal of Pharmacology evaluated CBDV’s potential to reduce nausea symptoms in animal models, finding promising results. This research suggests CBDV could become a valuable tool for managing nausea, particularly for those who need relief without impairment.

Perhaps the most studied application for CBDV is seizure management. Following the success of CBD-based Epidiolex, researchers have turned their attention to CBDV as a potential next-generation anticonvulsant.

While the seizure reduction results are promising, researchers note that further studies with larger sample sizes are needed to establish CBDV’s efficacy compared to existing treatments.

One of the most exciting frontiers for CBDV research is autism spectrum disorder (ASD). Several clinical trials are currently investigating whether CBDV can help manage certain symptoms associated with autism.

A 2019 study published in Translational Psychiatry examined CBDV’s effects on brain excitation and inhibition systems in adults with and without ASD. The research used magnetic resonance spectroscopy to measure how a single dose of CBDV affected brain chemistry—a crucial step in understanding how CBDV might help with ASD symptoms.

Beyond nausea, seizures, and autism, CBDV is being studied for several other conditions:

While pure CBDV products are not widely available, you can still benefit from this cannabinoid through full-spectrum and broad-spectrum CBD products. Here’s how:

1. Full-Spectrum CBD Oil: Contains trace amounts of CBDV along with other cannabinoids for the entourage effect
2. Broad-Spectrum CBD: Includes minor cannabinoids like CBDV without THC
3. Look for Lab Reports: Quality products will show cannabinoid profiles including CBDV content
4. Choose Quality Brands: Reputable manufacturers use whole-plant extracts that preserve minor cannabinoids
5. Consider Indica-Dominant Strains: Landrace indica strains naturally contain higher CBDV levels

Products like our Natura Remedy Broad Spectrum CBD Oil and Phyto Relax CBD Oil contain the full spectrum of cannabinoids, including trace CBDV, for comprehensive wellness support.

As clinical trials progress and more research emerges, CBDV is positioned to become an important therapeutic cannabinoid. Here’s what we can expect:

CBDV represents an exciting frontier in cannabinoid research. While it may not have the mainstream recognition of CBD or THC, its unique properties—particularly as an antiemetic and potential treatment for neurological conditions—make it a cannabinoid worth watching.

For now, the best way to experience CBDV’s benefits is through quality full-spectrum CBD products that contain trace amounts of this promising compound. As research advances and more CBDV-specific products become available, we’ll likely see this “hidden gem” cannabinoid take its rightful place in the wellness spotlight.

Whether you’re interested in CBDV for its anti-nausea properties, seizure research, or general wellness support, staying informed about the latest research will help you make the best decisions for your health journey.

Remember: cannabinoid science is rapidly evolving. What we know about CBDV today is just the beginning of understanding this remarkable compound’s full potential.

Explore Full-Spectrum CBD Products

While pure CBDV products are limited, you can benefit from this cannabinoid through our premium full-spectrum CBD offerings. Each product contains the full range of beneficial cannabinoids, including trace CBDV.

Shop Premium CBD: Browse our CBD Oils Collection for lab-tested, full-spectrum options that deliver the complete entourage effect.